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TNFRSF10B antibody

TNFRSF10B Reactivity: Human FACS, ELISA, Func Host: Mouse Monoclonal B-K29 unconjugated
Catalog No. ABIN1383912
  • Target See all TNFRSF10B Antibodies
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Reactivity
    • 98
    • 18
    • 4
    • 1
    • 1
    Human
    Host
    • 64
    • 38
    • 3
    • 1
    • 1
    • 1
    Mouse
    Clonality
    • 61
    • 44
    • 2
    Monoclonal
    Conjugate
    • 72
    • 10
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF10B antibody is un-conjugated
    Application
    • 74
    • 34
    • 30
    • 25
    • 17
    • 16
    • 15
    • 13
    • 12
    • 11
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), ELISA, Functional Studies (Func)
    Specificity
    Recognises a 42-46 kDa protein
    Purification
    Ion exchange chromatography
    Sterility
    0.22 μm filtered
    Immunogen
    Recombinant human TRAIL R2/Fc chimera,Myeloma X63/AG.8653 x Balb/c spleen cells
    Clone
    B-K29
    Isotype
    IgG1 kappa
    Biological Activity Comment
    Neutralizes TRAIL induced apoptosis of U937 cell line
    Top Product
    Discover our top product TNFRSF10B Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Phosphate-buffered saline. Sterile-filtered through 0.22 μm. Carrier and preservative free
    Preservative
    Without preservative
    Storage
    4 °C
    Storage Comment
    Stable at +2-8°C for 12 months. For longer storage freeze aliquots.
  • Chen, Chou, Chang, Chen: "Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 12, pp. 8030-9, (2008) (PubMed).

    Sato, Niessner, Kopecky, Frye, Goronzy, Weyand: "TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque." in: The Journal of experimental medicine, Vol. 203, Issue 1, pp. 239-50, (2006) (PubMed).

    Vermot-Desroches, Sergent, Bonnin, Wijdenes: "Characterization of monoclonal antibodies directed against trail or trail receptors." in: Cellular immunology, Vol. 236, Issue 1-2, pp. 86-91, (2005) (PubMed).

  • Target
    TNFRSF10B (Tumor Necrosis Factor Receptor Superfamily, Member 10b (TNFRSF10B))
    Alternative Name
    TRAIL R2 (TNFRSF10B Products)
    Synonyms
    TNFRSF10B antibody, dr5 antibody, cd262 antibody, killer antibody, trick2 antibody, trickb antibody, xDR-M1 antibody, xDR-M2 antibody, ztnfr9 antibody, trailr2 antibody, trick2a antibody, trick2b antibody, CD262 antibody, DR5 antibody, KILLER antibody, KILLER/DR5 antibody, TRAIL-R2 antibody, TRAILR2 antibody, TRICK2 antibody, TRICK2A antibody, TRICK2B antibody, TRICKB antibody, ZTNFR9 antibody, Ly98 antibody, MK antibody, tumor necrosis factor receptor superfamily, member 10b antibody, tumor necrosis factor receptor superfamily member 10b S homeolog antibody, tumor necrosis factor receptor superfamily member 10b L homeolog antibody, tumor necrosis factor receptor superfamily member 10b antibody, TNF receptor superfamily member 10b antibody, Tnfrsf10b antibody, TNFRSF10B antibody, tnfrsf10b.S antibody, tnfrsf10b.L antibody, tnfrsf10b antibody
    Background
    DR5, TRAIL R2
    Molecular Weight
    42-46 kDa
    Pathways
    p53 Signaling, Apoptosis, Positive Regulation of Endopeptidase Activity
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