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PCSK1N antibody (AA 34-130)

PCSK1N Reactivity: Human ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1385206
  • Target See all PCSK1N Antibodies
    PCSK1N (Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 34-130
    Reactivity
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 4
    • 3
    • 1
    Rabbit
    Clonality
    • 6
    • 2
    Polyclonal
    Conjugate
    • 8
    This PCSK1N antibody is un-conjugated
    Application
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human PROSAAS
    Isotype
    IgG
    Top Product
    Discover our top product PCSK1N Primary Antibody
  • Application Notes
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    PCSK1N (Proprotein Convertase Subtilisin/kexin Type 1 Inhibitor (PCSK1N))
    Alternative Name
    PROSAAS (PCSK1N Products)
    Synonyms
    PROSAAS antibody, SAAS antibody, Saas antibody, AI848336 antibody, KEP antibody, PEN antibody, PEN19 antibody, PEN20 antibody, Pan3 antibody, SAASCT antibody, bLEN antibody, lLEN antibody, proSAAS antibody, proprotein convertase subtilisin/kexin type 1 inhibitor antibody, PCSK1N antibody, Pcsk1n antibody
    Background

    Synonyms: b-LEN, b-PEN-LEN, b-SAAS, Big LEN, granin like neuroendocrine peptide, l-LEN, l-SAAS, N-proSAAS, PCSK1_HUMAN, Pcsk1n, pro-SAAS, Proprotein convertase 1 inhibitor, Proprotein convertase subtilisin/kexin type 1 inhibitor, PROSAAS, SAAS, SAAS CT1-49, SAAS CT25-40.

    Background: PCSK1N is a 260 amino acid protein that is both secreted and localized to the trans-Golgi network. Expressed in pancreas and brain, PCSK1N is thought to play a role in the control of the neuroendocrine secretory pathway and may also be involved in PCSK1 inhibition. The gene encoding PCSK1N maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination, as an X and a Y chromosome lead to normal male development, while two copies of an X chromosome lead to normal female development. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.

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