KCNE1 antibody (AA 64-100)

Catalog No. ABIN1385530

Product Details anti-KCNE1 Antibody

Target: KCNE1 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))

Binding Specificity: AA 64-100

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNE1 antibody is un-conjugated

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Dog, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNE1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-KCNE1 antibody (ABIN1385530)

Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).

Target Details for KCNE1

Target: KCNE1 (Potassium Voltage-Gated Channel, Isk-Related Family, Member 1 (KCNE1))

Alternative Name: KCNE1 (KCNE1 Products)

Synonyms: isk antibody, jlns antibody, mink antibody, jlns2 antibody, xkcne1 antibody, KCNE1 antibody, ISK antibody, JLNS antibody, JLNS2 antibody, LQT2/5 antibody, LQT5 antibody, MinK antibody, Isk antibody, m antibody, minK antibody, IsK antibody, nmf190 antibody, potassium channel, voltage gated subfamily E regulatory beta subunit 1 L homeolog antibody, potassium voltage-gated channel, Isk-related family, member 1 antibody, potassium voltage-gated channel subfamily E member 1 antibody, potassium voltage-gated channel subfamily E regulatory subunit 1 antibody, potassium voltage-gated channel, Isk-related subfamily, member 1 antibody, kcne1.L antibody, KCNE1 antibody, LOC474097 antibody, Kcne1 antibody

Background:

Synonyms: ISK, JLNS, LQT5, MinK, JLNS2, LQT2/5, Potassium voltage-gated channel subfamily E member 1, Delayed rectifier potassium channel subunit IsK, IKs producing slow voltage-gated potassium channel subunit beta Mink, Minimal potassium channel, KCNE1

Background: Ancillary protein that assembles as a beta subunit with a voltage-gated potassium channel complex of pore-forming alpha subunits. Modulates the gating kinetics and enhances stability of the channel complex. Assembled with KCNQ1/KVLQT1 is proposed to form the slowly activating delayed rectifier cardiac potassium (IKs) channel. The outward current reaches its steady state only after 5 seconds. Assembled with KCNH2/HERG may modulate the rapidly activating component of the delayed rectifying potassium current in heart (IKr).

Gene ID: 3753

UniProt: P15382

Pathways: Sensory Perception of Sound