Proprotein Convertase Subtilisin/kexin Type 2 (PCSK2) (AA 255-290) antibody

Details for Product No. ABIN1385997, Supplier: Log in to see
Antigen
  • NEC 2
  • NEC-2
  • NEC2
  • PC2
  • SPC2
  • PCSK2
  • 6330411F23Rik
  • AI839700
  • Nec-2
  • Nec2
  • Phpp-2
  • pc2
  • nec2
  • spc2
  • pcsk2
  • pcsk2-A
  • proprotein convertase subtilisin/kexin type 2
  • proprotein convertase subtilisin/kexin type 2 L homeolog
  • PCSK2
  • pcsk2
  • Pcsk2
  • pcsk2.L
Alternatives
anti-Human Proprotein Convertase Subtilisin/kexin Type 2 antibody for Western Blotting
Epitope
AA 255-290
14
8
4
4
4
3
3
2
2
2
2
2
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
65
32
27
6
3
3
3
2
2
2
2
2
1
1
Host
Rabbit
59
6
1
Clonality
Polyclonal
Conjugate
Un-conjugated
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
49
14
14
12
12
12
7
6
3
3
1
1
Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from human Proprotein Convertase 2
Isotype IgG
Purification Purified by Protein A.
Alternative Name Nec2/Proprotein Convertase 2/Pcsk2 (PCSK2 Antibody Abstract)
Background

Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells.

Synonyms: PC2, NEC2, SPC2, NEC 2, NEC-2, Neuroendocrine convertase 2, KEX2-like endoprotease 2, Prohormone convertase 2, Proprotein convertase 2, PCSK2

Gene ID 5126
UniProt P16519
Pathways Peptide Hormone Metabolism, cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity
Application Notes WB 1:100-1000
IHC-P 1:100-500
IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C
Expiry Date 12 months
Product cited in: van Rijn, Pouwer, Tryfonidou, Grinwis, van der Bend, Beukers, Vastenhout, Drouin, Penning, Meij: "Expression and clinical relevance of paired box protein 7 and sex determining region Y-box 2 in canine corticotroph pituitary adenomas." in: Veterinary journal (London, England : 1997), Vol. 204, Issue 3, pp. 315-21, 2015 (PubMed). Method employed by authors: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (Sample species: Dog (Canine)).

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