APPBP2 antibody (AA 201-300)

Catalog No. ABIN1386300

Product Details anti-APPBP2 Antibody

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Binding Specificity: AA 201-300

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APPBP2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Zebrafish

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human APPBP2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for APPBP2

Target: APPBP2 (Amyloid beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2 (APPBP2))

Alternative Name: APPBP2 (APPBP2 Products)

Synonyms: HS.84084 antibody, PAT1 antibody, 1300003O07Rik antibody, AI465480 antibody, zgc:76971 antibody, wu:fb78e11 antibody, wu:fc25c09 antibody, APPBP2 antibody, DKFZp459F0530 antibody, amyloid beta precursor protein binding protein 2 antibody, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 antibody, amyloid beta precursor protein (cytoplasmic tail) binding protein 2 S homeolog antibody, APPBP2 antibody, Appbp2 antibody, appbp2 antibody, appbp2.S antibody

Background:

Synonyms: amyloid beta precursor protein cytoplasmic tail binding protein 2, Amyloid beta precursor protein-binding protein 2, Amyloid protein binding protein 2, Amyloid protein-binding protein 2, APBP2_HUMAN, APP BP2, APP-BP2, Appbp2, PAT1, Ara67 Protein interacting with APP tail 1.

Background: APPBP2 is a hydrophilic, microtubule binding protein that functions in the trafficking of Beta-Amyloid precursor protein. It is expressed in a variety of cell types and localizes to the cytoplasm. APPBP2 shares homology with kinesin light chain. It consists of a coiled-coil domain, PKC phosphorylation sites, four imperfect C-terminal tandem repeats, eight tetratricopeptide repeats and N- and C-terminal globular structures. APPBP2 recognizes and binds to the basolateral sorting sequence (BaSS) present in the cytoplasmic domain of the Beta-Amyloid precursor protein. In addition, APPBP2 interacts with the androgen receptor and suppresses androgen signaling.

Gene ID: 10513

UniProt: Q92624