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CRIPT antibody (AA 21-80)

CRIPT Reactivity: Human ELISA, WB, IF (cc), IF (p), IHC (fro), IHC (p), ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN1386373
  • Target See all CRIPT Antibodies
    CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))
    Binding Specificity
    • 14
    • 6
    AA 21-80
    Reactivity
    • 22
    • 1
    • 1
    Human
    Host
    • 21
    • 1
    Rabbit
    Clonality
    • 21
    • 1
    Polyclonal
    Conjugate
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CRIPT antibody is un-conjugated
    Application
    • 17
    • 12
    • 12
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Predicted Reactivity
    Human,Mouse,Rat,Cow,Pig,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CRIPT
    Isotype
    IgG
    Top Product
    Discover our top product CRIPT Primary Antibody
  • Application Notes
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Expiry Date
    12 months
  • Target
    CRIPT (Cysteine-Rich PDZ-Binding Protein (CRIPT))
    Alternative Name
    CRIPT (CRIPT Products)
    Synonyms
    CRIPT antibody, hspc139 antibody, cript antibody, im:7137989 antibody, zgc:110618 antibody, 1200020A08Rik antibody, AA589469 antibody, CXXC repeat containing interactor of PDZ3 domain antibody, cysteine-rich PDZ-binding protein antibody, CXXC repeat containing interactor of PDZ3 domain S homeolog antibody, CRIPT antibody, cript antibody, LOC725850 antibody, cript.S antibody, Cript antibody
    Background

    Synonyms: CRIPT, CRIPT_HUMAN, Cysteine rich interactor of PDZ3, Cysteine rich PDZ binding protein, Cysteine-rich interactor of PDZ three, Cysteine-rich interactor of PDZ3, Cysteine-rich PDZ-binding protein, HSPC139, HSPC139 protein, Hypothetical protein CRIPT, Postsynaptic protein CRIPT.

    Background: The PSD-95/SAP 90 family of proteins, which are known to bind to and cluster various membrane proteins, are involved in the organization of synaptic structure. These proteins are physically and functionally linked to cytoskeletal and/or signaling proteins. CRIPT (for cysteine-rich interactor of PDZ three), a novel postsynaptic protein, binds specifically to the PDZ3 domain of PSD-95/SAP 90. CRIPT induces the recruitment of PSD-95/SAP 90 to microtubules, and it has been shown to bind directly to microtubules, indicating that it may be responsible for cytoskeletal anchoring of PSD-95/SAP 90. CRIPT is widely expressed outside of the brain and is highly conserved from animals to plants suggesting a wider role in regulating cytoskeleton-membrane associations.

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