SNAP29 antibody (AA 181-258)

Catalog No. ABIN1386535

Product Details anti-SNAP29 Antibody

Target: SNAP29 (Synaptosomal-Associated Protein, 29kDa (SNAP29))

Binding Specificity: AA 181-258

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAP29 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNAP29

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for SNAP29

Target: SNAP29 (Synaptosomal-Associated Protein, 29kDa (SNAP29))

Alternative Name: SNAP29 (SNAP29 Products)

Background:

Synonyms: SNAP 29, SNAP-29, SNAP29, SNP29_HUMAN, Soluble 29 kDa NSF attachment protein, Synaptosomal associated protein 29, Synaptosomal associated protein 29 kDa, Synaptosomal-associated protein 29, Vesicle membrane fusion protein SNAP 29, Vesicle membrane fusion protein SNAP29, Vesicle-membrane fusion protein SNAP-29, CEDNIK, FLJ21051.

Background: SNAP 29 is a 258 amino acid protein that localizes to the membrane and the cytoplasm, as well as to the cell junction, and contains one t-SNARE coiled-coil homology domain. Expressed in liver, heart, brain, kidney, placenta, lung, spleen, pancreas and skeletal muscle, SNAP 29 binds tightly to Syntaxins and, via this binding, is involved in membrane trafficking events. Defects in the gene encoding SNAP 29 are the cause of CEDNIK syndrome, a neurocutaneous syndrome that is associated with cerebral dysgenesis, neuropathy, ichthyosis and palmoplantar keratoderma. The gene encoding SNAP 29 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.

Gene ID: 9342