GNAL antibody (AA 21-130)

Catalog No. ABIN1386650

Product Details anti-GNAL Antibody

Target: GNAL (Guanine Nucleotide Binding Protein, alpha Stimulating, Olfactory Type (GNAL))

Binding Specificity: AA 21-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GNAL antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Cow,Sheep,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GNAL

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GNAL

Target: GNAL (Guanine Nucleotide Binding Protein, alpha Stimulating, Olfactory Type (GNAL))

Alternative Name: GNAL (GNAL Products)

Synonyms: DYT25 antibody, zgc:103521 antibody, 2610011C15Rik antibody, 9630020G10Rik antibody, AI843190 antibody, Galphaolf antibody, Gna10 antibody, Golf antibody, Olf antibody, RGD1305940 antibody, G protein subunit alpha L antibody, guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type antibody, guanine nucleotide binding protein, alpha stimulating, olfactory type antibody, GNAL antibody, gnal antibody, Gnal antibody

Background:

Synonyms: Adenylate cyclase stimulating G alpha protein, olfactory type, Adenylate cyclase stimulating G alpha protein, olfactory type, Adenylate cyclase-stimulating G alpha protein, Gnal, GNAL_HUMAN, Guanine nucleotide binding protein G protein, alpha activating activity polypeptide, olfactory type, Guanine nucleotide binding protein G protein, alpha stimulating activity polypeptide, olfactory type, Guanine nucleotide binding protein Golf subunit alpha, Guanine nucleotide-binding protein Golf subunit alpha, olfactory type.

Background: Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors (1). Each of a very broad range of receptors specifically detects an extracellular stimulus (a photon, pheromone, odorant, hormone or neurotransmitter) while the effectors (e.g., adenyl cyclase), which act to generate one or more intracellular messengers, are less numerous. In mammals, G protein alpha, beta and gamma polypeptides are encoded by at least 16, 4 and 7 genes, respectively (2-5). Most interest in G proteins has been focused on their alpha subunits, since these proteins bind and hydrolyze GTP and most obviously regulate the activity of the best studied effectors. More recent evidence, however, has established an important regulatory role for the beta gamma subunits (6-8). The Gs subfamily of G alpha subunits includes two closely related proteins, Ga s and Ga olf, which respectively stimulate adenylate cyclase and mediate response to olfactory stimuli (9).