GABRG3 antibody (AA 31-130)

Catalog No. ABIN1386675

Product Details anti-GABRG3 Antibody

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Binding Specificity: AA 31-130

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRG3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GABRG3/GABA A Receptor gamma 3

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for GABRG3

Target: GABRG3 (gamma-aminobutyric Acid (GABA) A Receptor, gamma 3 (GABRG3))

Alternative Name: GABRG3/GABA A Receptor gamma 3 (GABRG3 Products)

Synonyms: GABRG3 antibody, B230362M20Rik antibody, Gabrg-3 antibody, gamma-aminobutyric acid type A receptor gamma3 subunit antibody, gamma-aminobutyric acid receptor subunit gamma-3 antibody, gamma-aminobutyric acid type A receptor gamma 3 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3 antibody, GABRG3 antibody, gabrg3 antibody, LOC100011485 antibody, Gabrg3 antibody

Background:

Synonyms: GABAA receptor, GABAA receptor subunit gamma 3, GABR G3, GABRG 3, GABRG3, Gamma aminobutyric acid GABA A receptor gamma 3, Gamma aminobutyric acid A receptor gamma 3, Gamma aminobutyric acid receptor subunit gamma 3, GBRG3_HUMAN.

Background: GAD-65 and GAD-67, glutamate decarboxylases, function to catalyze the production of GABA (gamma-aminobutyric acid). In the central nervous system GABA functions as the main inhibitory transmitter by increasing a Cl- conductance that inhibits neuronal firing. GABA has been shown to activate both ionotropic (GABAA) and metabotropic (GABAB) receptors as well as a third class of receptors called GABAC. Both GABAA and GABAC are ligand-gated ion channels, however, they are structurally and functionally distinct. Members of the GABAA receptor family include GABAA R Alpha 1-6, GABAA R Beta 1-3, GABAA R Gamma 1-3, GABAA R Delta, GABAA R Epsilon, GABAA R Zeta 1 and GABAA R Zeta 2. The GABAB family is composed of GABAB R1 Alpha and GABAB R1 Beta. GABA transporters have also been identified and include GABA T-1, GABA T-2 and GABA T-3 (also designated GAT-1, -2, and -3). The GABA transporters function to terminate GABA action.