CHRNA6 antibody (AA 101-200)

Catalog No. ABIN1386688

Product Details anti-CHRNA6 Antibody

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNA6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CHRNA6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CHRNA6

Target: CHRNA6 (Cholinergic Receptor, Nicotinic, alpha 6 (CHRNA6))

Alternative Name: CHRNA6 (CHRNA6 Products)

Synonyms: Acra6 antibody, Nica6 antibody, si:dkey-234d14.1 antibody, CHNRA6 antibody, cholinergic receptor nicotinic alpha 6 subunit antibody, cholinergic receptor, nicotinic, alpha polypeptide 6 antibody, cholinergic receptor, nicotinic, alpha 6 antibody, Chrna6 antibody, CHRNA6 antibody, chrna6 antibody

Background:

Synonyms: AChR-alpha6, Acra6, Cholinergic receptor nicotinic alpha 6, Cholinergic receptor nicotinic alpha polypeptide 6, CHRNA 6, nAChR alpha 6, NACHRA6, Neuronal acetylcholine receptor subunit alpha 6, Nicotinic acetylcholine receptor alpha6, ACHA6_HUMAN.

Background: Members of the ligand-gated ion channel receptor family are characterized by their fast transmitting response to neurotransmitters. Two important members of this family are the nicotinic acetylcholine and glutamate receptors, both of which are composed of five homologous subunits forming a transmembrane aqueous pore. These transmembrane receptors change conformation in response to their cognate neurotransmitter. Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing ions to move through the pore. AChR alpha 6, also designated cholinergic nicotinic receptor alpha polypeptide 6, is a neuronal acetylcholine receptor protein expressed in respiratory mucosa. AChR alpha 6 is also selectively expressed on dopaminergic terminals, where it complexes with AChR Beta 2 and AChR alpha 4.