KCNF1 antibody (AA 161-260)

Catalog No. ABIN1386733

Product Details anti-KCNF1 Antibody

Target: KCNF1 (Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1))

Binding Specificity: AA 161-260

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCNF1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for KCNF1

Target: KCNF1 (Potassium Voltage-Gated Channel, Subfamily F, Member 1 (KCNF1))

Alternative Name: KCNF1 (KCNF1 Products)

Synonyms: kcnf1 antibody, si:dkey-65b13.5 antibody, KCNF1 antibody, ik8 antibody, kh1 antibody, kcnf antibody, kv5.1 antibody, IK8 antibody, KCNF antibody, KV5.1 antibody, kH1 antibody, Gm1182 antibody, Kv5.1 antibody, Kh1 antibody, potassium voltage-gated channel, subfamily F, member 1a antibody, potassium voltage-gated channel modifier subfamily F member 1 antibody, potassium channel, voltage gated modifier subfamily F, member 1 antibody, potassium voltage-gated channel, subfamily F, member 1 antibody, kcnf1a antibody, KCNF1 antibody, kcnf1 antibody, Kcnf1 antibody

Background:

Synonyms: IK 8, IK8, KCNF 1, KCNF, Kcnf1, KCNF1_HUMAN, kH 1, kH1, KV5.1, Potassium voltage-gated channel subfamily F member 1, MGC33316, Potassium channel KH1, Potassium channel Kv5.1, Potassium voltage gated channel subfamily F member 1, Potassium voltage-gated channel subfamily F member 1, Voltage gated potassium channel subunit Kv5.1, Voltage-gated potassium channel subunit Kv5.1.

Background: KCNF1 is a multi-pass membrane-bound protein that acts as an ion channel and is generally expressed as a heterotetramer of potassium channeling proteins. Formerly known as kH1, KCNF1 is usually found as a heteromer with three other potassium channel proteins, KCNG3, KV6.3 and KCNV2. As a potassium channel protein, KCNF1 plays a role in regulating apoptosis and proliferation of pulmonary artery smooth muscle (PASM) cells. Bone morphogenetic proteins (BMPs) restrict proliferation and can induce apoptosis in normal human PASM cells and will upregulate expression of KCNF1 in PASM cells in vitro. KCNF1 is expressed in heart, brain, liver, skeletal muscle, kidney and pancreas.