BRP44L antibody (AA 1-80)

Catalog No. ABIN1386834

Product Details anti-BRP44L Antibody

Target: BRP44L (Brain Protein 44-Like (BRP44L))

Binding Specificity: AA 1-80

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BRP44L antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human BRP44L

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for BRP44L

Target: BRP44L (Brain Protein 44-Like (BRP44L))

Alternative Name: BRP44L (BRP44L Products)

Synonyms: CGI-129 antibody, MGC90013 antibody, brp44l antibody, brp44la antibody, brp44lb antibody, MGC64469 antibody, MPC1 antibody, BRP44L antibody, MPYCD antibody, dJ68L15.3 antibody, 0610006G08Rik antibody, 3830411I18Rik antibody, Brp44l antibody, mitochondrial pyruvate carrier 1 antibody, mitochondrial pyruvate carrier 1 S homeolog antibody, uncharacterized protein antibody, mitochondrial pyruvate carrier 1 L homeolog antibody, brain protein 44-like antibody, mpc1 antibody, mpc1.S antibody, LOC542696 antibody, MPC1 antibody, mpc1.L antibody, LOC100164048 antibody, LOC100167201 antibody, Mpc1 antibody

Background:

Synonyms: Apoptosis regulating basic protein, Brain protein 44 like protein, CGI129, HSPC040, PNAS115, MPC1_HUMAN.

Background: BRP44L, also known as HSPC040 or CGI-129, is a 109 amino acid mitochondrial protein belonging to the UPF0041 family. The gene that encodes BRP44L maps to human chromosome 6. Making up nearly 6 % of the human genome, chromosome 6 contains around 1,200 genes within 170 million base pairs of sequence. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer suggesting the presence of a cancer susceptibility locus. Porphyria cutanea tarda is associated with chromosome 6 through the HFE gene which, when mutated, predisposes an individual to developing this porphyria. Notably, the PARK2 gene, which is associated with Parkinson's disease, and the genes encoding the major histocompatiblity complex proteins, which are key molecular components of the immune system and determine predisposition to rheumatic diseases, are also located on chromosome 6. Stickler syndrome, 21-hydroxylase deficiency and maple syrup urine disease are also associated with genes on chromosome 6. A bipolar disorder susceptibility locus has been identified on the q arm of chromosome 6.

Gene ID: 51660

Pathways: Warburg Effect