NR6A1 antibody (AA 251-350)
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- Target See all NR6A1 Antibodies
- NR6A1 (Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1))
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Binding Specificity
- AA 251-350
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This NR6A1 antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Predicted Reactivity
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human GCNF
- Isotype
- IgG
- Top Product
- Discover our top product NR6A1 Primary Antibody
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- NR6A1 (Nuclear Receptor Subfamily 6, Group A, Member 1 (NR6A1))
- Alternative Name
- GCNF (NR6A1 Products)
- Synonyms
- GCNF antibody, GCNF1 antibody, NR61 antibody, RTR antibody, hGCNF antibody, hRTR antibody, 1700113M01Rik antibody, Gcnf antibody, NCNF antibody, gcnf antibody, xEmGCNF antibody, gcnf1 antibody, nr61 antibody, rtr antibody, xGCNF antibody, NR6A1 antibody, GCNF-B antibody, si:ch211-167p9.1 antibody, zC167P9.1 antibody, zgc:114189 antibody, nr6a1 antibody, zfGCNF antibody, nuclear receptor subfamily 6 group A member 1 antibody, nuclear receptor subfamily 6, group A, member 1 antibody, nuclear receptor subfamily 6 group A member 1 S homeolog antibody, nuclear receptor subfamily 6, group A, member 1b antibody, nuclear receptor subfamily 6, group A, member 1a antibody, NR6A1 antibody, Nr6a1 antibody, nr6a1.S antibody, nr6a1 antibody, nr6a1b antibody, nr6a1a antibody
- Background
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Synonyms: GCNF 1, GCNF, GCNF1, Germ cell nuclear factor, hGCNF, hRTR, NR 61, NR61, NR6A1, NR6A1_HUMAN, Nuclear receptor subfamily 6 group A member 1, Orphan nuclear receptor NR6A1, Retinoic acid receptor related testis associated receptor, Retinoid receptor related testis specic receptor, Retinoid receptor-related testis-specic receptor, RTR.
Background: Germ cell nuclear factor (GCNF) is an orphan member of the nuclear receptor gene superfamily that influences neurogenesis and germ cell development. GCNF can homodimerize and bind DNA. GCNF regulates paracrine interaction between the oocyte and somatic cells by regulating the expression of BMP-15 and GDF-9, to affect female fertility. GCNF is present in spermatocytes and round spermatids of adult male mouse testis, northern blot and ribonuclease protection assays have shown GCNF is predominant in the testis. The gene expresses three alternatively spliced transcript variants.
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway
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