SLC40A1 antibody (AA 331-430)

Catalog No. ABIN1387819

Product Details anti-SLC40A1 Antibody

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Binding Specificity: AA 331-430

Reactivity: Human, Mouse, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SLC40A1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Chicken, Human, Mouse

Predicted Reactivity: Rat,Dog,Pig,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLC40A1/FPN1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SLC40A1 antibody (ABIN1387819)

Zhang, Li, Liao, Zhang, Lu, Luo: "Effect of iron source on iron absorption and gene expression of iron transporters in the ligated duodenal loops of broilers." in: Journal of animal science, Vol. 95, Issue 4, pp. 1587-1597, (2017) (PubMed).

Rychtarcikova, Lettlova, Tomkova, Korenkova, Langerova, Simonova, Zjablovskaja, Alberich-Jorda, Neuzil, Truksa: "Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism." in: Oncotarget, Vol. 8, Issue 4, pp. 6376-6398, (2016) (PubMed).

Target Details for SLC40A1

Target: SLC40A1 (Solute Carrier Family 40 (Iron-Regulated Transporter), Member 1 (SLC40A1))

Alternative Name: SLC40A1 (SLC40A1 Products)

Background:

Synonyms: FPN1, HFE4, MTP1, IREG1, MST079, MSTP079, SLC11A3, Solute carrier family 40 member 1, Ferroportin-1, Iron-regulated transporter 1, SLC40A1

Background: May be involved in iron export from duodenal epithelial cell and also in transfer of iron between maternal and fetal circulation. Mediates iron efflux in the presence of a ferroxidase (hephaestin and/or ceruloplasmin).

Gene ID: 30061

UniProt: Q9NP59

Pathways: Transition Metal Ion Homeostasis