LSAMP antibody (AA 51-150) (Alexa Fluor 488)

Catalog No. ABIN1389214

Product Details anti-LSAMP Antibody (Alexa Fluor 488)

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Binding Specificity: AA 51-150

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LSAMP antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LSAMP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LSAMP

Target: LSAMP (Limbic System-Associated Membrane Protein (LSAMP))

Alternative Name: LSAMP (LSAMP Products)

Synonyms: chLAMP antibody, IGLON3 antibody, LAMP antibody, 5430428I19 antibody, AW046674 antibody, B130007O04Rik antibody, D930023J12Rik antibody, Lam antibody, Lamp antibody, limbic system-associated membrane protein antibody, LSAMP antibody, Lsamp antibody

Background:

Synonyms: IgLON family member 3, IGLON3, Lam, LAMP, Limbic system associated membrane protein, Limbic system associated membrane protein precursor, Limbic system-associated membrane protein, LSAMP, LSAMP_HUMAN.

Background: LSAMP is a neuronal surface glycoprotein found in cortical and subcortical regions of the limbic system expressed on the surface of somata and proximal dendrites of neurons. It is a member of the immunoglobulin (Ig) superfamily and belongs to the IgLON subfamily of cell adhesion molecules. LSAMP contains three Ig domains and a glycosylphosphatidylinositol anchor. It is a highly conserved protein between rodents and humans (99 % sequence identity) and it is involved in the regulation of neurite outgrowth and mediation of proper circuit formation of limbic pathways. This suggests that LSAMP plays an important role in the development and function of the limbic system. In addition, LSAMP may function as a tumor suppressor in renal carcinomas.