DERL1 antibody (AA 111-220) (Biotin)
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- Target See all DERL1 Antibodies
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
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Binding Specificity
- AA 111-220
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This DERL1 antibody is conjugated to Biotin
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Cross-Reactivity
- Human
- Predicted Reactivity
- Mouse,Rat,Dog,Cow,Sheep,Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human DERLIN-1
- Isotype
- IgG
- Top Product
- Discover our top product DERL1 Primary Antibody
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anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 224-251), (C-Term) antibody
DERL1 Reactivity: Human, Mouse WB, IHC (p), FACS Host: Rabbit Polyclonal RB22770 unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 186-251) antibodyDERL1 Reactivity: Human WB, IHC (p), IF Host: Rabbit Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 111-220) antibodyDERL1 Reactivity: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC Host: Rabbit Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 224-251) antibodyDERL1 Reactivity: Human, Mouse WB, IHC, IHC (p), FACS Host: Rabbit Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (C-Term) antibodyDERL1 Reactivity: Human, Mouse, Dog, Chicken, Cow, Rat, Primate, Zebrafish (Danio rerio) WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 222-251), (C-Term) antibodyDERL1 Reactivity: Human, Mouse WB, IHC (p), FACS, EIA Host: Rabbit Polyclonal unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 134-233) antibodyDERL1 Reactivity: Human WB, ELISA Host: Mouse Monoclonal 1B9 unconjugated
anti-Der1-Like Domain Family, Member 1 (DERL1) (AA 182-251) antibodyDERL1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
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IHC-P 1:200-400
IHC-F 1:100-500 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
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- Target
- DERL1 (Der1-Like Domain Family, Member 1 (DERL1))
- Alternative Name
- DERLIN-1 (DERL1 Products)
- Background
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Synonyms: Derlin1, Derlin1, Derlin 1, DER1, DER-1, DER 1, DERL1_HUMAN.
Background: Degradation in endoplasmic reticulum proteins, also designated Derlins or DERtrins, are crucial for the degradation of misfolded endoplasmic reticulum (ER) luminal proteins. Derlin proteins are multi-pass membrane proteins localizing to the ER. Derlins are involved in transferring misfolded proteins from the ER to the cytosol, where the misfolded proteins are destroyed in an ubiquitin-dependent manner by the proteasome. In the case of cytomegalovirus infection, Derlin-1, as opposed to Derlins-2 and -3, is involved in the export of MHC class I heavy chains from the ER via its interaction with the viral protein US11. Derlins may also be important for cell proliferation.
- Gene ID
- 79139
- UniProt
- Q9BUN8
- Pathways
- ER-Nucleus Signaling
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