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AACS antibody (AA 182-228) (Alexa Fluor 555)

AACS Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1390949
  • Target See all AACS Antibodies
    AACS (Acetoacetyl-CoA Synthetase (AACS))
    Binding Specificity
    • 14
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 182-228
    Reactivity
    • 33
    • 7
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Human
    Host
    • 32
    • 1
    Rabbit
    Clonality
    • 33
    Polyclonal
    Conjugate
    • 14
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AACS antibody is conjugated to Alexa Fluor 555
    Application
    • 27
    • 13
    • 12
    • 12
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human AACS
    Isotype
    IgG
    Top Product
    Discover our top product AACS Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    AACS (Acetoacetyl-CoA Synthetase (AACS))
    Alternative Name
    AACS/ACSF1 (AACS Products)
    Synonyms
    sur-5 antibody, An08g04090 antibody, AO090001000376 antibody, ACSF1 antibody, SUR-5 antibody, 2210408B16Rik antibody, SUR5 antibody, zgc:56105 antibody, acetoacetyl-CoA synthetase antibody, bll4282 antibody, acetoacetyl-coa synthetase antibody, acetoacetate--CoA ligase antibody, acetoacetate-CoA ligase antibody, Acetoacetyl-CoA synthetase antibody, AACS antibody, LOC590598 antibody, aacs antibody, bll4282 antibody, Pfl01_3080 antibody, h16_A2860 antibody, Mflv_1473 antibody, ANI_1_594074 antibody, Pput_2653 antibody, VIBHAR_RS20435 antibody, AOR_1_648164 antibody, CC1G_04522 antibody, LACBIDRAFT_230952 antibody, PLES_33261 antibody, PA1997 antibody, OB0504 antibody, CBU_0766 antibody, acsA2 antibody, Sde_0006 antibody, Plav_1154 antibody, AZC_2243 antibody, SGR_RS30655 antibody, Aacs antibody, sur-5 antibody
    Background

    Synonyms: Acetoacetyl-CoA synthetase, ACSF1, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS_HUMAN.

    Background: ACSF1 is a 672 amino acid protein belonging to the ATP-dependent AMP-binding enzyme family. Encoded by a gene that maps to human chromosome 12q24.31, ACSF1 is highly expressed in kidney, heart and brain, and shows similar neural expression as HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase). Existing as three alternatively spliced isoforms, ACSF1 participates in ATP binding, ligase activity, acetoacetate-CoA ligase activity and nucleotide binding. The ACSF1 promoter is a known PPAR?target gene, with the nuclear receptor recruited to the ACSF1 promoter by direct interaction with stimulating protein-1 (Sp1). ACSF1 activates acetoacetate and is highly regulated by modulators that affect HMGCR and cholesterol biosynthesis.

    Gene ID
    65985
    Pathways
    Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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