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BBS9 antibody (AA 244-320) (Alexa Fluor 350)

BBS9 Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1391697
  • Target See all BBS9 Antibodies
    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
    Binding Specificity
    • 14
    • 8
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    AA 244-320
    Reactivity
    • 30
    • 15
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Rat
    Host
    • 44
    Rabbit
    Clonality
    • 44
    Polyclonal
    Conjugate
    • 11
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This BBS9 antibody is conjugated to Alexa Fluor 350
    Application
    • 20
    • 19
    • 12
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Dog,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human BBS9
    Isotype
    IgG
    Top Product
    Discover our top product BBS9 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    BBS9 (Bardet-Biedl Syndrome 9 (BBS9))
    Alternative Name
    BBS9 (BBS9 Products)
    Synonyms
    b1 antibody, B1 antibody, C18 antibody, D1 antibody, PTHB1 antibody, RGD1308472 antibody, E130103I17Rik antibody, Bardet-Biedl syndrome 9 antibody, bardet-biedl syndrome 9 antibody, Bardet-Biedl syndrome 9 (human) antibody, BBS9 antibody, bbs9 antibody, Bbs9 antibody
    Background

    Synonyms: B1, D1, C18, PTHB1, Protein PTHB1, Bardet-Biedl syndrome 9 protein, Parathyroid hormone-responsive B1 gene protein, BBS9

    Background: The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to RAB3IP/Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane. Required for proper BBSome complex assembly and its ciliary localization.

    Gene ID
    27241
    UniProt
    Q3SYG4
    Pathways
    Hedgehog Signaling
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