FAM163A antibody (AA 121-167) (Biotin)

Catalog No. ABIN1392889

Product Details anti-FAM163A Antibody (Biotin)

Target: FAM163A (Family with Sequence Similarity 163, Member A (FAM163A))

Binding Specificity: AA 121-167

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FAM163A antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NDSP

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for FAM163A

Target: FAM163A (Family with Sequence Similarity 163, Member A (FAM163A))

Alternative Name: NDSP/FAM163A (FAM163A Products)

Synonyms: C1orf76 antibody, NDSP antibody, RP11-12M5.2 antibody, A230106N23Rik antibody, family with sequence similarity 163 member A antibody, family with sequence similarity 163, member A antibody, FAM163A antibody, Fam163a antibody

Background:

Synonyms: C1orf76, Chromosome 1 open reading frame 76, F163A_HUMAN, Fam163a, hypothetical protein MGC16664, NDSP, Neuroblastoma derived secretory protein, Neuroblastoma-derived secretory protein, Protein FAM163A

Background: Chromosome 1 is the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1. A breakpoint has been identified in 1q which disrupts the DISC1 gene and is linked to schizophrenia. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma. The C1orf76 gene product has been provisionally designated C1orf76 pending further characterization.