FNBP1L antibody (AA 101-200) (Alexa Fluor 350)

Catalog No. ABIN1393641

Product Details anti-FNBP1L Antibody (Alexa Fluor 350)

Target: FNBP1L (Formin Binding Protein 1-Like (FNBP1L))

Binding Specificity: AA 101-200

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FNBP1L antibody is conjugated to Alexa Fluor 350

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FNBP1L/TOCA1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for FNBP1L

Target: FNBP1L (Formin Binding Protein 1-Like (FNBP1L))

Alternative Name: FNBP1L/TOCA1 (FNBP1L Products)

Synonyms: C1orf39 antibody, TOCA1 antibody, 2610318I01Rik antibody, AW548221 antibody, RGD1305386 antibody, Toca-1 antibody, zgc:100923 antibody, toca1 antibody, toca-1 antibody, MGC132162 antibody, fnbp1l antibody, formin binding protein 1 like antibody, formin binding protein 1-like antibody, formin binding protein 1 like L homeolog antibody, formin binding protein 1 like S homeolog antibody, FNBP1L antibody, Fnbp1l antibody, fnbp1l antibody, fnbp1l.L antibody, fnbp1l.S antibody

Background:

Synonyms: C1orf39, FBP1L_HUMAN, FNBP 1L, fnbp1l, Formin binding protein 1 like, Formin-binding protein 1-like, TOCA 1, Toca-1, TOCA1, Transducer of Cdc42 dependent actin assembly 1 , Transducer of Cdc42 dependent actin assembly protein 1, Transducer of Cdc42-dependent actin assembly protein 1.

Background: TOCA-1 is a 605 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to cytoplasmic vesicles and the cell membrane, and contains one FCH domain, one REM repeat and one SH3 domain. Existing as multiple alternatively spliced isoforms, TOCA-1 interacts with CDC42 and is required for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. Additionally, TOCA-1 is involved in membrane invagination, tubule formation and Actin polymerization. The gene encoding TOCA-1 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8 % of the human genome.