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Paralemmin antibody (AA 130-230) (Biotin)

PALM Reactivity: Mouse WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1394785
  • Target See all Paralemmin (PALM) Antibodies
    Paralemmin (PALM)
    Binding Specificity
    • 14
    • 6
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 130-230
    Reactivity
    • 18
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Mouse
    Host
    • 23
    • 4
    Rabbit
    Clonality
    • 24
    • 3
    Polyclonal
    Conjugate
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Paralemmin antibody is conjugated to Biotin
    Application
    • 23
    • 13
    • 13
    • 12
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Paralemmin 1
    Isotype
    IgG
    Top Product
    Discover our top product PALM Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    Paralemmin (PALM)
    Alternative Name
    Paralemmin 1 (PALM Products)
    Synonyms
    PALM antibody, palm antibody, zgc:110136 antibody, paralemmin antibody, paralemmin 1a antibody, paralemmin S homeolog antibody, PALM antibody, palm1a antibody, palm antibody, palm.S antibody, Palm antibody
    Background

    Synonyms: KIAA0270, PALM, PALM_HUMAN, Paralemmin, Paralemmin1,Paralemmin-1.

    Background: Paralemmin, also called Paralemmin-1 or PALM, is a widely expressed peripheral membrane protein that is involved in cell structure and shape. A hydrophobic protein, Paralemmin is anchored to the cytoplasmic side of the cell membrane via di-palmitoylation and prenylation of its C-terminal cysteine cluster. Functioning at the synapse to regulate neuronal plasticity and plasma membrane dynamics, Paralemmin can bind to the dopamine receptor D3, thereby reducing D3 expression and subsequent adenylate cyclase activity. Overexpression of Paralemmin induces fibroblasts to extend long filopodia and to assume extreme cell shapes, suggesting involvement in the formation and stabilization of the plasma membrane. Two isoforms of Paralemmin exists due to alternative splicing events.

    Pathways
    cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling
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