P2RX6 antibody (AA 55-160) (Biotin)

Catalog No. ABIN1395217

Product Details anti-P2RX6 Antibody (Biotin)

Target: P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))

Binding Specificity: AA 55-160

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RX6 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2RX6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for P2RX6

Target: P2RX6 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 6 (P2RX6))

Alternative Name: P2RX6 (P2RX6 Products)

Synonyms: P2RXL1 antibody, P2X6 antibody, P2XM antibody, P2rxl1 antibody, P2x6 antibody, P2xm antibody, Rnap2x6 antibody, purinergic receptor P2X 6 antibody, purinergic receptor P2X, ligand-gated ion channel, 6 antibody, P2X purinoceptor 6 antibody, P2RX6 antibody, P2rx6 antibody, LOC100051842 antibody, LOC100588488 antibody

Background:

Synonyms: ATP receptor, P2RX6, P2RX6_HUMAN, P2RXL1, P2X purinoceptor 6, P2X6, P2XM, Purinergic receptor, Purinergic receptor P2X like 1, Purinergic receptor P2X-like 1, Skeletal muscle expressed P2X.

Background: The P2X receptor family is comprised of ligand-gated ion channels that allow for the increased permeability of calcium into the cell in response to extracellular ATP. The seven P2X receptors, P2X1-P2X7, form either homomeric or heteromeric channels or both. They are characterized by intracellular amino- and carboxy-termini. P2X receptors are expressed in a wide variety of tissues, including neurons, prostate, bladder, pancreas, colon, testis and ovary. The major function of the P2X receptors is to mediate synaptic transmissions between neurons and to other tissues via the binding of extracellular ATP, which acts as a neurotransmitter. The P2X receptors may be involved in the onset of necrosis or apoptosis after prolonged exposure to high concentrations of extracellular ATP.