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CPXM1 antibody (AA 251-350) (Biotin)

CPXM1 Reactivity: Human WB, ELISA, IHC (p), IHC (fro) Host: Rabbit Polyclonal Biotin
Catalog No. ABIN1398523
  • Target See all CPXM1 Antibodies
    CPXM1 (Carboxypeptidase X (M14 Family), Member 1 (CPXM1))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-350
    Reactivity
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 19
    • 2
    Rabbit
    Clonality
    • 19
    • 2
    Polyclonal
    Conjugate
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CPXM1 antibody is conjugated to Biotin
    Application
    • 21
    • 13
    • 13
    • 5
    • 3
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CPXM
    Isotype
    IgG
    Top Product
    Discover our top product CPXM1 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C for 12 months.
    Expiry Date
    12 months
  • Target
    CPXM1 (Carboxypeptidase X (M14 Family), Member 1 (CPXM1))
    Alternative Name
    CPXM (CPXM1 Products)
    Synonyms
    CPX1 antibody, CPXM antibody, AA986902 antibody, Cpx-1 antibody, Cpx1 antibody, Cpxm antibody, carboxypeptidase X, M14 family member 1 antibody, carboxypeptidase X 1 (M14 family) antibody, CPXM1 antibody, Cpxm1 antibody
    Background

    Synonyms: Carboxypeptidase X M14 family member 1, Carboxypeptidase X member 1, CPX 1, CPX1, CPXM 1, CPXM1, Metallocarboxypeptidase CPX 1, Probable carboxypeptidase X1, CPXM1_HUMAN.

    Background: CPXM (carboxypeptidase X, member 1) belongs to the peptidase M14 family. However, no carboxypeptidase activity has yet been detected. It may be involved in cell-cell interactions.Members of the M14 metallocarboxypeptidase protein family serve many diverse functions and are divided into three subfamilies based on structure, function and amino acid sequence similarity. Belonging to the N/E subfamily, CPXM (metallocarboxypeptidase CPX-1) is a 734 amino acid protein that contains a F5/8 type C domain and likely binds one zinc ion per subunit. Most members of the N/E subfamily contain several domains, including an active carboxypeptidase domain and signal peptide, and are thought to function mostly in protein-protein interactions and/or protein-membrane interactions, thereby targeting the protein to specific locations within the secretory pathway. CPXM is a unique member of this subfamily in that it does not appear to exhibit any enzymatic activity due to lack of several active-site residues that are present in the catalytic domain of other members of the N/E subfamily. Studies showing that CPXM expression is regulated during osteoclastogenesis suggest that CPXM may play a role in osteoclast differentiation. There are two isoforms of CPXM which are a result of alternative splicing events.

    Gene ID
    56265
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