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UBE2J2 antibody (AA 1-100) (Alexa Fluor 488)

UBE2J2 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 488
Catalog No. ABIN1398754
  • Target See all UBE2J2 Antibodies
    UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))
    Binding Specificity
    • 14
    • 4
    • 2
    • 2
    • 2
    • 1
    AA 1-100
    Reactivity
    • 35
    • 14
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 32
    • 3
    Rabbit
    Clonality
    • 35
    Polyclonal
    Conjugate
    • 15
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBE2J2 antibody is conjugated to Alexa Fluor 488
    Application
    • 27
    • 12
    • 12
    • 8
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human
    Predicted Reactivity
    Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human UBE2J2
    Isotype
    IgG
    Top Product
    Discover our top product UBE2J2 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    UBE2J2 (Ubiquitin-Conjugating Enzyme E2, J2 (UBE2J2))
    Alternative Name
    UBE2J2 (UBE2J2 Products)
    Synonyms
    NCUBE-2 antibody, NCUBE2 antibody, PRO2121 antibody, 1200007B18Rik antibody, 2400008G19Rik antibody, 5730472G04Rik antibody, AL022923 antibody, Ubc6 antibody, Ubc6p antibody, zgc:162164 antibody, ubiquitin conjugating enzyme E2 J2 antibody, ubiquitin-conjugating enzyme E2J 2 antibody, ubiquitin-conjugating enzyme E2, J2 antibody, ubiquitin-conjugating enzyme E2 J2 antibody, ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast) antibody, ubiquitin conjugating enzyme E2 J2 L homeolog antibody, UBE2J2 antibody, Ube2j2 antibody, LOC5574000 antibody, CpipJ_CPIJ008956 antibody, ube2j2 antibody, uce2 antibody, ube2j2.L antibody, LOC100067387 antibody
    Background

    Synonyms: NCUBE-2, NCUBE2, Non-canonical ubiquitin-conjugating enzyme 2, UB2J2_HUMAN, UBC6, UBC6 homolog, ube2j2, Ubiquitin-conjugating enzyme E2 J2.

    Background: Ubiquitination is an important molecular mechanism by which abnormal or short-lived proteins are targeted for degradation by the concerted efforts of at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2J2 (Ubiquitin-conjugating enzyme E2 J2), also known as NCUBE2 (Non-canonical ubiquitin-conjugating enzyme 2), is a 259 amino acid single pass type IV membrane protein that that belongs to the E2 ubiquitin-conjugating enzyme family and is involved in protein degradation. Localized to the membrane of the endoplasmic reticulum (ER), UBE2J2 catalyzes the attachment of ubiquitin to misfolded membrane proteins, thereby targeting them for proteasomal destruction. This ATP-dependent reaction yields AMP, a diphosphate and a ubiquitin-tagged protein and may be a method of quality control within the ER. Two isoforms of UBE2J2 exist due to alternative splicing events.

    Gene ID
    118424
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