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APLP2 antibody (Amyloid beta (A4) Precursor-Like Protein 2) AA 501-600 (Alexa Fluor 350) Primary Antibody

APLP2 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350
Catalog No. ABIN1399227
$476.30
Plus shipping costs $45.00
100 μL
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  • Target See all APLP2 Antibodies
    APLP2
    Binding Specificity
    • 14
    • 14
    • 10
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 501-600
    Reactivity
    • 85
    • 27
    • 26
    • 1
    Human
    Host
    • 79
    • 6
    Rabbit
    Clonality
    • 78
    • 7
    Polyclonal
    Conjugate
    • 43
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    This APLP2 antibody is conjugated to Alexa Fluor 350
    Application
    • 54
    • 36
    • 35
    • 12
    • 12
    • 10
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Pig,Horse,Chicken
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human APLP2
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    APLP2
    Alternative Name
    APLP2 (APLP2 Products)
    Synonyms
    HAI, MT-SP1, MTSP1, PRSS14, SNC19, TADG15, TMPRSS14, APLP-2, APPH, APPL2, CDEBP, AI790698, Apph, WALPLP2, aplp2 B, APLP2, si:dkey-11k4.3, aplp2 A, MGC86389, suppression of tumorigenicity 14, amyloid beta precursor like protein 2, amyloid beta (A4) precursor-like protein 2, amyloid beta (A4) precursor-like protein 2 S homeolog, amyloid beta (A4) precursor-like protein 2 L homeolog, ST14, APLP2, Aplp2, aplp2.S, aplp2, aplp2.L
    Background

    APLP2 is a human sperm membrane protein which contains a segment with high homology to the transmembrane-cytoplasmic domains of APP found in brain plaques of Alzheimer disease patients. The human amyloid precursor-like protein APLP2 is a highly conserved homolog of a sequence-specific DNA-binding mouse protein with an important function in the cell cycle. The gene which encodes APLP2 maps to human chromosome 11q24.May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.

    Subcellular location: Nucleus, Cell membrane

    Synonyms: amyloid beta A4 precursor like protein 2, Amyloid like protein 2, amyloid precursor protein homolog HSD2, Amyloid protein homolog, Amyloid-like protein 2, APLP-2, Aplp2, APLP2_HUMAN, APPH, APPL2, CDEBP, CDEI box binding protein, CDEI box-binding protein.

    Gene ID
    Pathways
    EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Feeding Behaviour
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