STIM1 antibody (Stromal Interaction Molecule 1) AA 85-180 (Alexa Fluor 647) Primary Antibody
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- Target See all STIM1 Antibodies
- STIM1
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Binding Specificity
- AA 85-180
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Reactivity
- Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This STIM1 antibody is conjugated to Alexa Fluor 647
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Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Specificity
- May cross react with STIM2
- Predicted Reactivity
- Human,Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human STIM1
- Isotype
- IgG
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C/-80 °C
- Storage Comment
- Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
- Expiry Date
- 12 months
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- Target
- STIM1
- Alternative Name
- STIM1 (STIM1 Products)
- Synonyms
- stim1, MGC76045, STIM1, si:dkey-24p1.5, MGC154748, si:ch211-112l17.2, Stim1, D11S4896E, GOK, TAM, SIM, stromal interaction molecule 1, stromal interaction molecule 1a, stromal interaction molecule 1 L homeolog, stromal interaction molecule 1b, STIM1, stim1, stim1a, stim1.L, stim1b, Stim1
- Background
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Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: GOK, TAM, TAM1, IMD10, STRMK, D11S4896E, Stromal interaction molecule 1, STIM1
- Gene ID
- UniProt
- Q13586
- Pathways
- TCR Signaling, BCR Signaling