GRAMD3 antibody (GRAM Domain Containing 3) AA 121-220 (Alexa Fluor 488)

Catalog No. ABIN1399846

Product Details anti-GRAMD3 Antibody

Target: GRAMD3

Binding Specificity: AA 121-220

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRAMD3 antibody is conjugated to Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GRAMD3/NS3TP2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C/-80 °C

Storage Comment: Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles

Expiry Date: 12 months

Target Details for GRAMD3

Target: GRAMD3

Alternative Name: GRAMD3 (GRAMD3 Products)

Synonyms: NS3TP2, 9030613F08Rik, 9130427A09Rik, AW061306, RGD1311016, GRAM domain containing 3, GRAM domain containing 2B, GRAMD3, GRAMD2B, Gramd3

Background:

GRAMD3 is a 432 amino acid protein that contains one GRAM domain and is encoded by a gene that maps to human chromosome 5q23.2. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6 % of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.

Synonyms: FLJ21313, GRAM domain containing 3, GRAM domain-containing protein 3, GRAM domain-containing protein 3_ GRAM3_HUMAN, Gramd3, HCV NS3-transactivated protein 2, hepatitis C virus nonstructural protein 3 transactivating protein 2, NS3TP2.

Gene ID: