LGR6 antibody (AA 401-500) (Alexa Fluor 647)

Catalog No. ABIN1400004

Product Details anti-LGR6 Antibody (Alexa Fluor 647)

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Binding Specificity: AA 401-500

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGR6 antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human LGR6

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for LGR6

Target: LGR6 (Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 6 (LGR6))

Alternative Name: LGR6 (LGR6 Products)

Synonyms: LGR6 antibody, GPCR antibody, VTS20631 antibody, A530037C04Rik antibody, D830026M09 antibody, RGD1560339 antibody, leucine rich repeat containing G protein-coupled receptor 6 antibody, leucine-rich repeat-containing G protein-coupled receptor 6 antibody, LGR6 antibody, Lgr6 antibody

Background:

Synonyms: GPCR, VTS20631, Leucine-rich repeat-containing G-protein coupled receptor 6, LGR6, UNQ6427/PRO213

Background: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

Gene ID: 59352

UniProt: Q9HBX8