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CDK14 antibody (Cyclin-Dependent Kinase 14) (Alexa Fluor 555) Primary Antibody

CDK14 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1400711
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all CDK14 Antibodies
    CDK14
    Reactivity
    • 70
    • 49
    • 18
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 67
    • 3
    Rabbit
    Clonality
    • 70
    Polyclonal
    Conjugate
    • 25
    • 7
    • 6
    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDK14 antibody is conjugated to Alexa Fluor 555
    Application
    • 57
    • 41
    • 21
    • 12
    • 8
    • 4
    • 3
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CDK14/PFTK1
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    CDK14
    Alternative Name
    CDK14 (CDK14 Products)
    Synonyms
    PFTK1, PFTAIRE1, Pftk1, mKIAA0834, pftaire1, pftk1, cyclin dependent kinase 14, cyclin-dependent kinase 14, cyclin-dependent kinase 14 L homeolog, CDK14, Cdk14, cdk14.L
    Background

    Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport.

    Synonyms: cdk14, CDK14_HUMAN, Cell division protein kinase 14, Cyclin-dependent kinase 14, hPFTAIRE1, KIAA0834, mKIAA0834, PFTAIRE1, PFTK1, Serine/threonine protein kinase PFTAIRE 1, Serine/threonine-protein kinase PFTAIRE-1.

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