Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

SH3RF1 antibody (SH3 Domain Containing Ring Finger 1) (Alexa Fluor 647) Primary Antibody

SH3RF1 Reactivity: Human, Mouse, Rat IF (p) Host: Rabbit Polyclonal Alexa Fluor 647
Catalog No. ABIN1401156
$476.30
Plus shipping costs $45.00
100 μL
local_shipping Shipping to: United States
Delivery in 11 to 16 Business Days
  • Target See all SH3RF1 Antibodies
    SH3RF1
    Reactivity
    • 24
    • 20
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 21
    • 3
    Rabbit
    Clonality
    • 22
    • 2
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH3RF1 antibody is conjugated to Alexa Fluor 647
    Application
    • 13
    • 12
    • 6
    • 3
    • 3
    • 1
    Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human SH3MD2/RNF142
    Isotype
    IgG
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C/-80 °C
    Storage Comment
    Store at -20°C, for long storage, store at -80°C. Avoid multiple freeze-thaw cycles
    Expiry Date
    12 months
  • Target
    SH3RF1
    Alternative Name
    RNF142 (SH3RF1 Products)
    Synonyms
    SH3MD2, posh, xPOSH, rnf142, sh3md2, MGC135632, MGC189605, POSH, RNF142, 2200003J05Rik, Posh, R75531, Sh3md2, si:ch211-114c9.2, si:dkey-15j16.4, wu:fi42f11, SH3 domain containing ring finger 1, SH3 domain containing ring finger 1 S homeolog, SH3RF1, sh3rf1, sh3rf1.S, Sh3rf1
    Background

    SH3MD2 acts as a scaffold protein, contributes to Rac-induced signal transduction such as JNKs (MAPK8 and MAPK9) activation and induces apoptosis. Within a signaling complex, it probably recruits protein kinases such as MAP3K10 or MAP3K11 which are in turn activated leading to the sequential activation of MAP2K4, MAP2K7 and JNKs (MAPK8 and MAPK9). SH3MD2 may be involved in targeting of HIV-1 GAG and GAG-POL polyproteins to the plasma membrane. This gene encodes a protein containing an N-terminus RING-finger, four SH3 domains, and a region implicated in binding of the Rho GTPase Rac. Via the RING-finger, the encoded protein has been shown to function as an ubiquitin-protein ligase involved in protein sorting at the trans-Golgi network. The encoded protein may also act as a scaffold for the c-Jun N-terminal kinase signaling pathway, facilitating the formation of a functional signaling module. There are two named isoforms.

    Synonyms: Plenty of SH3 domains, Plenty of SH3s, POSH, Ring finger protein 142, RNF 142, RNF142, SH3 domain containing ring finger 1, SH3 domain containing RING finger protein 1, SH3MD2, SH3 multiple domains 2, SH3RF1.

    Gene ID
You are here:
help Support