SERPINB11 antibody (Biotin)

Catalog No. ABIN1401493

This Rabbit Polyclonal antibody specifically detects SERPINB11 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for SERPINB11 antibody (Biotin) (ABIN1401493)

Target: SERPINB11 (Serine (Or Cysteine) Peptidase Inhibitor, Clade B (Ovalbumin), Member 11 (SERPINB11))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SERPINB11 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-SERPINB11 Antibody (Biotin)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SERPINB11

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for SERPINB11

Target: SERPINB11 (Serine (Or Cysteine) Peptidase Inhibitor, Clade B (Ovalbumin), Member 11 (SERPINB11))

Alternative Name: SERPINB11

Background:

Synonyms: EPIPIN, Serine or cysteine proteinase inhibitor clade B ovalbumin member 11 antibody Serpin B11 antibody Serpin peptidase inhibitor clade B ovalbumin member 11 antibody SERPINB11d antibody SERPINB11e antibody SERPINB11f, SPB11_HUMAN.

Background: The serine proteinase inhibitors (serpins) compose a superfamily of proteins with a diverse set of functions, including the control of blood coagulation, complement activation, programmed cell death and development. Serpins are secreted glycoproteins that contain a stretch of peptide that mimics a true substrate for a corresponding serine protease. SerpinB11 (serpin peptidase inhibitor, clade B (ovalbumin), member 11), also known as EPIPIN or SERPIN11, is a 392 amino acid cytoplasmic protein that belongs to the Ov-serpin subfamily and serpin family. Like other members of the serpin family, SerpinB11 has been identified as a noninhibitory intracellular protein. The gene encoding SerpinB11 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas.

Gene ID: 89778