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CACNA1S antibody (AA 951-1001) (Alexa Fluor 555)

CACNA1S Reactivity: Human, Mouse, Rat IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 555
Catalog No. ABIN1405475
  • Target See all CACNA1S Antibodies
    CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 951-1001
    Reactivity
    Human, Mouse, Rat
    Host
    • 22
    • 2
    Rabbit
    Clonality
    • 23
    • 1
    Polyclonal
    Conjugate
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CACNA1S antibody is conjugated to Alexa Fluor 555
    Application
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CACNA1S
    Isotype
    IgG
    Top Product
    Discover our top product CACNA1S Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CACNA1S (Calcium Channel, Voltage-Dependent, L Type, alpha 1S Subunit (CACNA1S))
    Alternative Name
    CACNA1S (CACNA1S Products)
    Synonyms
    CACNA1S antibody, cav1.1 antibody, ca(v)1.1 antibody, CACNL1A3 antibody, CCHL1A3 antibody, Cav1.1 antibody, HOKPP antibody, HOKPP1 antibody, MHS5 antibody, TTPP1 antibody, hypoPP antibody, AW493108 antibody, Cchl1a3 antibody, fmd antibody, mdg antibody, sj antibody, caV1.1 antibody, calcium voltage-gated channel subunit alpha1 S antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit S homeolog antibody, calcium channel, voltage-dependent, L type, alpha 1S subunit antibody, CACNA1S antibody, cacna1s.S antibody, Cacna1s antibody
    Background

    Synonyms: Voltage-dependent L-type calcium channel subunit alpha-1S, Calcium channel, L type, alpha-1 polypeptide, isoform 3, skeletal muscle, Voltage-gated calcium channel subunit alpha Cav1.1, CACNA1S, CACH1, CACN1, CACNL1A3

    Background: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1S gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, benzothiazepines, and by omega-agatoxin-IIIA (omega-Aga-IIIA). They are however insensitive to omega-conotoxin-GVIA (omega-CTx-GVIA) and omega-agatoxin-IVA (omega-Aga-IVA). Calcium channels containing the alpha-1S subunit play an important role in excitation-contraction coupling in skeletal muscle.

    Gene ID
    779
    UniProt
    Q13698
    Pathways
    Skeletal Muscle Fiber Development
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