C11orf65 antibody (Alexa Fluor 555)

Catalog No. ABIN1405565

Product Details anti-C11orf65 Antibody (Alexa Fluor 555)

Target: C11orf65 (Chromosome 11 Open Reading Frame 65 (C11orf65))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C11orf65 antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C11orf65

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for C11orf65

Target: C11orf65 (Chromosome 11 Open Reading Frame 65 (C11orf65))

Alternative Name: C11orf65 (C11orf65 Products)

Synonyms: AU017961 antibody, chromosome 11 open reading frame 65 antibody, chromosome 11 open reading frame 65 L homeolog antibody, chromosome 14 open reading frame, human C11orf65 antibody, RIKEN cDNA 4930550C14 gene antibody, similar to RIKEN cDNA 4930550C14 antibody, C11orf65 antibody, c11orf65.L antibody, C14H11orf65 antibody, 4930550C14Rik antibody, RGD1311251 antibody

Background:

Synonyms: Chromosome 11 open reading frame 65, Hypothetical protein LOC160140, CK065_HUMAN.

Background: C11orf65, also known as MGC33948, is a 313 amino acid protein that is encoded by a gene located on human chromosome 11. With approximately 135 million base pairs and 1,400 genes, chromosome 11 makes up around 4 % of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and _ thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.

Gene ID: 160140