Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) (AA 161-260) antibody (Cy5)

Catalog No. ABIN1406752

Product Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Binding Specificity: AA 161-260

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy5

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Sheep,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human STAU2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Double-stranded RNA-binding protein Staufen homolog 2 (STAU2)

Alternative Name: STAU2 (STAU2 Products)

Synonyms: r-staufen protein antibody, staufen (RNA binding protein) homolog 2 (Drosophila) antibody, staufen double-stranded RNA binding protein 2 antibody, Stau2 antibody

Background:

Synonyms: Double stranded RNA binding protein Staufen homolog 2, MGC119606, STAU 2, STAU2, STAU-2, Staufen Drosophila, RNA-binding protein homolog 2, Staufen homolog 2, Staufen RNA binding protein homolog 2, Staufen, RNA binding protein, homolog 2 Drosophila, 39K2, 39K3, DKFZp781K0371, STAU2_HUMAN.

Background: Staufen homolog 2 is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. Staufen homolog 2 shares 48.5 % and 59.9 % similarity with drosophila and human staufen, respectively. The exact function of Staufen homolog 2 is not known, but since it contains 3 copies of conserved dsRNA binding domain, it could be involved in double-stranded RNA binding events. Several transcript variants encoding different isoforms have been found for this gene.