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TANC1 antibody (AA 31-130) (Cy5.5)

TANC1 Reactivity: Human IF (cc), IF (p) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN1406789
  • Target See all TANC1 Antibodies
    TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
    Binding Specificity
    • 14
    • 2
    • 1
    • 1
    AA 31-130
    Reactivity
    • 18
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TANC1 antibody is conjugated to Cy5.5
    Application
    • 12
    • 12
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human TANC1
    Isotype
    IgG
    Top Product
    Discover our top product TANC1 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    TANC1 (Tetratricopeptide Repeat, Ankyrin Repeat and Coiled-Coil Containing 1 (TANC1))
    Alternative Name
    TANC1 (TANC1 Products)
    Synonyms
    ROLSB antibody, TANC antibody, 1200003E16Rik antibody, Tanc antibody, mKIAA1728 antibody, tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 antibody, TANC1 antibody, Tanc1 antibody
    Background

    Synonyms: ROLSB, Protein TANC1, Rolling pebbles homolog B, TANC, Tanc1, TANC1_HUMAN, Tetratricopeptide repeat ankyrin repeat and coiled coil containing 1, Tetratricopeptide repeat ankyrin repeat and coiled coil domain containing protein 1, TPR domain ankyrin repeat and coiled coil containing.

    Background: TANC (tetratricopeptide repeat, ankyrin repeat and coiled-coil domain-containing protein), also known as TANC1, is a 1,861 amino acid postsynaptic cell membrane protein that contains eleven ANK repeats, three TPR repeats and belongs to the TANC family. Considered a scaffolding component in the postsynaptic density, TANC interacts with TNIK, SAPAP1, Alpha-internexin, CaMKII, NMDA 2 and GluR-1. It is also thought that TANC interacts directly with SAP 97, PSD-95 and Homer. Upon stimulation by Rap 2, MINK1 and TNIK may phosphorylate TANC. The TANC gene encodes two alternatively spliced isoforms, contains approximately 264,025 bases and maps to human chromosome 2q24.2. Making up approximately 8 % of the human genome, chromosome 2 consists of 237 million bases and encodes over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2 including Harlequin icthyosis, sitosterolemia and Alstr syndrome.

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