Astrotactin 2 antibody (ASTN2) (HRP)

Details for Product anti-ASTN2 Antibody No. ABIN1406996
Antigen
  • bA67K19.1
  • ASTN2
  • 1d8
  • Astnl
  • bM452J22.1
  • astrotactin 2
  • astrotactin-2
  • ASTN2
  • LOC702370
  • astn2
  • Astn2
Reactivity
Human, Mouse (Murine), Rat (Rattus)
36
32
17
1
Host
Rabbit
43
4
Clonality
Polyclonal
Conjugate
This Astrotactin 2 antibody is conjugated to HRP
4
4
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
32
24
13
6
2
1
1
Options
Immunogen KLH conjugated synthetic peptide derived from human ASTN2
Isotype IgG
Purification Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others Astrotactin 2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Astn2 (ASTN2 Antibody Abstract)
Background

Neuronal migration of the central nervous system is a specialized form of cell motility that takes place in the laminar structure of the cortical regions of brain. Astrotactin is a neuronal cell surface protein expressed on postmitotic neuronal precursors in the cerebellum, hippocampus, cerebrum, and olfactory bulb. Astrotactin 2 is a paralog of Astrotactin. Astrotactin mediates neuron-astroglial interactions and is also implicated in synaptic development as well as many other neuronal activities. Astrotactin has three epidermal growth factor repeat domains and two fibronectin type III repeat domains. The human Astrotactin gene shows extensive homology to the mouse Astrotactin gene. Mutations in the Astrotactin gene are linked to neuronal migration defects in both species.

Subcellular location: Extracellular

Synonyms: Astn2, Astn-2, Astn 2, ASTN2_HUMAN, Astrotactin 2, Astrotactin2, Astrotactin-2, bA67K19.1, KIAA0634.

Application Notes WB 1:100-1000
IHC-P 1:100-500
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % Gentamicin.
Preservative Gentamicin sulfate
Precaution of Use This product contains Gentamicin sulfate: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
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