HOXA4 antibody (AA 151-250) (HRP)

Catalog No. ABIN1408304

Product Details anti-HOXA4 Antibody (HRP)

Target: HOXA4 (Homeobox A4 (HOXA4))

Binding Specificity: AA 151-250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXA4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Sheep,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HOXA4

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HOXA4

Target: HOXA4 (Homeobox A4 (HOXA4))

Alternative Name: HOXA4 (HOXA4 Products)

Synonyms: HOX1 antibody, HOX1D antibody, AV206827 antibody, Hox-1.4 antibody, HOX1.4 antibody, HOXA4 antibody, HOXA-4 antibody, hox1d antibody, Hox1r2 antibody, hox1.4 antibody, homeobox A4 antibody, homeobox A4 S homeolog antibody, homeo box A4 antibody, HOXA4 antibody, Hoxa4 antibody, hoxa4.S antibody

Background:

Synonyms: Dfd like protein, Homeo box A4, Homeobox A4, Homeobox protein Hox-1.4, Homeobox protein Hox-1D, Homeobox protein Hox-A4, Hox 1.4 like protein, hox-1.4, hox-1d, HOX1, HOX1D, HOXA4, HXA4_HUMAN.

Background: The Hox homeobox genes encode proteins that are transcriptional regulators with an established role in embryonic development. HoxA4 (homeobox A4), also known as HOX1D or HOX1, is a 320 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. Expressed in the embryonic nervous system, HoxA4 functions as a sequence-specific DNA-binding transcription factor that is part of a regulatory mechanism that provides cells with positional identities during development. Via its ability to bind DNA, HoxA4 plays an important role in the regulation of gene expression, as well as morphogenesis and differentiation. The gene encoding HoxA4 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5 % of the human genome. Defects in some of the genes localized to chromosome 7 have been linked to Osteogenesis imperfecta, Williams-Beuren syndrome, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.