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CADPS2 antibody (AA 435-510) (HRP)

CADPS2 Reactivity: Human ELISA, IHC (fro) Host: Rabbit Polyclonal HRP
Catalog No. ABIN1409528
  • Target See all CADPS2 Antibodies
    CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 435-510
    Reactivity
    • 18
    • 3
    • 2
    Human
    Host
    • 18
    Rabbit
    Clonality
    • 18
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CADPS2 antibody is conjugated to HRP
    Application
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CADPS2
    Isotype
    IgG
    Top Product
    Discover our top product CADPS2 Primary Antibody
  • Application Notes
    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Handling Advice
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CADPS2 (Ca++-Dependent Secretion Activator 2 (CADPS2))
    Alternative Name
    CADPS2 (CADPS2 Products)
    Synonyms
    RGD1559440 antibody, A230044C21Rik antibody, Caps-2 antibody, Caps2 antibody, Cpd2 antibody, caps antibody, cpd2 antibody, zgc:110135 antibody, calcium dependent secretion activator 2 antibody, Ca2+-dependent activator protein for secretion 2 antibody, Ca++-dependent secretion activator 2 antibody, CADPS2 antibody, Cadps2 antibody, cadps2 antibody
    Background

    Synonyms: Cadps2, Calcium-dependent activator protein for secretion 2, Calcium-dependent secretion activator 2, CAPS2, CAPS2_HUMAN.

    Background: Calcium-dependent secretion activators (CAPS-1 and CAPS-2) are calcium-binding proteins that direct neurotransmitter and neuropeptide-filled vesicles to the cell membrane for secretory granule exocytosis. Both CAPS-1 and CAPS-2 are expressed primarily in the brain where they regulate the secretion of various substances. The CAPS proteins contain a PH domain that is essential for regulation of exocytosis, as well as regulation of phospholipid binding. Through their regulation of neurotrophin release from granule cells, CAPS proteins help to regulate cell fate during neuronal development. CAPS-1 is thought to regulate catecholamine release from neuronal cells, while CAPS-2 is thought to regulate release of both brain-derived neurotrophic factor and neurotrophin-3 from granule cells. Defects in the genes encoding CAPS-1 and CAPS-2 are implicated in impaired cerebral development and autism.

    Pathways
    Synaptic Vesicle Exocytosis
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