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APH1B antibody (AA 51-150) (Cy5)

Aph1b Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy5
Catalog No. ABIN1410358
  • Target See all APH1B (Aph1b) Antibodies
    APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
    Binding Specificity
    • 14
    • 4
    • 2
    • 1
    • 1
    • 1
    AA 51-150
    Reactivity
    • 19
    • 10
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Mouse
    Host
    • 24
    Rabbit
    Clonality
    • 24
    Polyclonal
    Conjugate
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This APH1B antibody is conjugated to Cy5
    Application
    • 21
    • 12
    • 12
    • 9
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse
    Predicted Reactivity
    Human,Rat,Dog,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Aph-1b
    Isotype
    IgG
    Top Product
    Discover our top product Aph1b Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    APH1B (Aph1b) (Anterior Pharynx Defective 1 Homolog B (Aph1b))
    Alternative Name
    Aph-1b (Aph1b Products)
    Synonyms
    APH-1B antibody, PRO1328 antibody, PSFL antibody, TAAV688 antibody, APH-1B' antibody, 2310057K14Rik antibody, Aph1c antibody, aph-1 homolog B, gamma-secretase subunit antibody, aph-1 homolog B, gamma secretase subunit antibody, aph1 homolog B, gamma secretase subunit antibody, APH1B antibody, Aph1b antibody
    Background

    Synonyms: PSFL, APH-1B, PRO1328, TAAV688, Gamma-secretase subunit APH-1B, Aph-1beta, Presenilin-stabilization factor-like, APH1B, UNQ688/PRO1328

    Background: Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.

    Gene ID
    83464
    UniProt
    Q8WW43
    Pathways
    Notch Signaling, Neurotrophin Signaling Pathway
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