P2RY11 antibody (AA 71-170) (HRP)

Catalog No. ABIN1412882

Product Details anti-P2RY11 Antibody (HRP)

Target: P2RY11 (Purinergic Receptor P2Y, G-Protein Coupled, 11 (P2RY11))

Binding Specificity: AA 71-170

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This P2RY11 antibody is conjugated to HRP

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human

Predicted Reactivity: Cow,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human P2Y11

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for P2RY11

Target: P2RY11 (Purinergic Receptor P2Y, G-Protein Coupled, 11 (P2RY11))

Alternative Name: P2Y11 (P2RY11 Products)

Synonyms: p2y11 antibody, P2Y11 antibody, purinergic receptor P2Y, G-protein coupled, 11 L homeolog antibody, purinergic receptor P2Y, G-protein coupled, 11 antibody, purinergic receptor P2Y11 antibody, p2ry11.L antibody, p2ry11 antibody, P2RY11 antibody

Background:

Synonyms: P2RY11, P2Y purinoceptor 11, P2Y11, P2Y11 receptor, P2Y11_HUMAN, Purinergic receptor P2Y G protein coupled 11, Purinergic receptor P2Y11.

Background: P2Y purinoceptor 11 (P2Y11) is a 374 amino acid protein belonging to the G-protein coupled receptor one family. P2Y11 is a multi-pass cell membrane protein that acts as a receptor for both ATP and ATD coupled to G proteins. Due to these interactions, P2Y11 is involved in phosphatidylinositol-calcium and adenylyl cyclase pathways. Induced by DMSO and retinoic acid, P2Y11 is highly expressed in spleen tissue. A putative trans-splicing event involving the gene that encodes P2Y11 and an upstream gene encoding PPAN has been found to result in a fusion protein, designated PPAN-P2RY11.

Gene ID: 5032

UniProt: Q96G91

Pathways: cAMP Metabolic Process