DNAJC7 antibody (AA 221-320) (HRP)

Catalog No. ABIN1416052

Product Details anti-DNAJC7 Antibody (HRP)

Target: DNAJC7 (DnaJ (Hsp40) Homolog, Subfamily C, Member 7 (DNAJC7))

Binding Specificity: AA 221-320

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DNAJC7 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DNAJC7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for DNAJC7

Target: DNAJC7 (DnaJ (Hsp40) Homolog, Subfamily C, Member 7 (DNAJC7))

Alternative Name: DNAJC7 (DNAJC7 Products)

Synonyms: CCRP antibody, dnajc7 antibody, MGC89403 antibody, BEST:LD24941 antibody, CG4599 antibody, Dmel\\CG4599 antibody, EU3220 antibody, Tpr-2 antibody, Trp2 antibody, dTPR2 antibody, dTpr2 antibody, dtpr2 antibody, dtrpr2 antibody, tpr2 antibody, DJ11 antibody, DJC7 antibody, TPR2 antibody, TTC2 antibody, 2010003F24Rik antibody, 2010004G07Rik antibody, Ttc2 antibody, mDj11 antibody, mTpr2 antibody, wu:fj58b08 antibody, zgc:85806 antibody, DnaJ heat shock protein family (Hsp40) member C7 antibody, Tetratricopeptide repeat protein 2 antibody, DnaJ (Hsp40) homolog, subfamily C, member 7 antibody, Dnajc7 antibody, DNAJC7 antibody, dnajc7 antibody, Tpr2 antibody

Background:

Synonyms: DnaJ homolog subfamily C member 7, Tetratricopeptide repeat protein 2, TPR repeat protein 2, TPR2, TTC2, DNJC7_HUMAN.

Background: The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are in-volved in the regulation of protein degradation, exocytsis and endocytosis. DnaJC7 (DnaJ homolog subfamily C member 7), also known as TPR2, TTC2 or DANJC7, is ubiquitously expressed, with highest expression in testis, liver, heart and brain.

Gene ID: 7266

UniProt: Q99615