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CLEC4E antibody (AA 51-150) (Cy3)

CLEC4E Reactivity: Human, Rat WB, FACS, IF (cc), IF (p) Host: Rabbit Polyclonal Cy3
Catalog No. ABIN1417487
  • Target See all CLEC4E Antibodies
    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
    Binding Specificity
    • 15
    • 7
    • 3
    • 1
    • 1
    AA 51-150
    Reactivity
    • 29
    • 16
    • 2
    Human, Rat
    Host
    • 23
    • 6
    Rabbit
    Clonality
    • 24
    • 5
    Polyclonal
    Conjugate
    • 11
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CLEC4E antibody is conjugated to Cy3
    Application
    • 24
    • 15
    • 13
    • 12
    • 12
    • 5
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Rat
    Predicted Reactivity
    Mouse,Cow,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human CLECSF9/CLEC4E
    Isotype
    IgG
    Top Product
    Discover our top product CLEC4E Primary Antibody
  • Application Notes
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    CLEC4E (C-Type Lectin Domain Family 4, Member E (CLEC4E))
    Alternative Name
    CLEC 4E (CLEC4E Products)
    Synonyms
    CLECSF9 antibody, MINCLE antibody, C86253 antibody, Clecsf9 antibody, Mincle antibody, CLEC4E antibody, C-type lectin domain family 4 member E antibody, C-type lectin domain family 4, member e antibody, C-type lectin domain family 4, member E antibody, CLEC4E antibody, Clec4e antibody, LOC611538 antibody
    Background

    Synonyms: C type lectin domain family 4 member E, C type lectin superfamily member 9, C-type calcium dependent carbohydrate recognition domain lectin superfamily member 9, C-type lectin domain family 4 member E, C-type lectin superfamily member 9, CLC4E_HUMAN, CLEC 4E, CLEC4E Clec4e, CLECSF9, Macrophage inducible C type lectin, Macrophage-inducible C-type lectin, MINCLE.

    Background: C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B.

    Gene ID
    26253
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