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MARCH9 antibody (Cy5.5)

MARCH9 Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN1420045
  • Target See all MARCH9 Antibodies
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    Reactivity
    • 41
    • 24
    • 21
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 38
    • 2
    Rabbit
    Clonality
    • 39
    • 2
    Polyclonal
    Conjugate
    • 13
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MARCH9 antibody is conjugated to Cy5.5
    Application
    • 40
    • 16
    • 12
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human MARCH9
    Isotype
    IgG
    Top Product
    Discover our top product MARCH9 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    MARCH9 (Membrane-Associated Ring Finger (C3HC4) 9 (MARCH9))
    Alternative Name
    MARCH9 (MARCH9 Products)
    Synonyms
    Rnf179 antibody, March-IX antibody, MARCH-IX antibody, RNF179 antibody, AI608492 antibody, BC019560 antibody, membrane associated ring-CH-type finger 9 antibody, membrane associated ring-CH-type finger 9 S homeolog antibody, membrane-associated ring finger (C3HC4) 9 antibody, March9 antibody, march9.S antibody, MARCH9 antibody, march9 antibody
    Background

    Synonyms: E3 ubiquitin protein ligase MARCH9, MARCH IX, Membrane associated RING CH protein IX, membrane associated ring finger C3HC4 9, Membrane associated RING finger protein 9, RING finger protein 179, RNF179, MARH9_HUMAN.

    Background: Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). MARCH9 (membrane-associated ring finger (C3HC4) 9), also known as RNF179, is a 346 amino acid multi-pass membrane protein that localizes to the golgi apparatus and contains one RING-CH-type zinc finger. Expressed ubiquitously, MARCH9 exists as a homodimer and functions as an E3 ubiquitin-protein ligase that accepts a ubiquitin residue from an E2 ubiquitin-conjugating enzyme and is thought to promote the degradation of target proteins, such as CD4 and MHC-I. Multiple isoforms of MARCH9 exist due to alternative splicing events.

    Gene ID
    92979
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