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HECA antibody (AA 260-310) (Cy7)

HECA Reactivity: Human, Mouse, Rat WB, IF (p) Host: Rabbit Polyclonal Cy7
Catalog No. ABIN1422050
  • Target See all HECA Antibodies
    HECA (Headcase Homolog (HECA))
    Binding Specificity
    • 14
    • 1
    • 1
    • 1
    • 1
    AA 260-310
    Reactivity
    • 23
    • 21
    • 21
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 22
    • 1
    Rabbit
    Clonality
    • 23
    Polyclonal
    Conjugate
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HECA antibody is conjugated to Cy7
    Application
    • 23
    • 12
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Human, Mouse, Rat
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human HECA
    Isotype
    IgG
    Top Product
    Discover our top product HECA Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    HECA (Headcase Homolog (HECA))
    Alternative Name
    HECA (HECA Products)
    Synonyms
    HECA antibody, si:dkey-34f16.2 antibody, HDC antibody, HDCL antibody, HHDC antibody, dJ225E12.1 antibody, Gm869 antibody, hdc homolog, cell cycle regulator antibody, Heca antibody, HECA antibody, heca antibody
    Background

    Synonyms: HDCL, Gm869, HDC, HDC_HUMAN, Headcase homolog Drosophila, Headcase protein homolog, HECA, hHDC.

    Background: HECA, also known as headcase homolog, HDC, HDCL or HHDC, is a 543 amino acid mammalian homolog of the Drosophila headcase protein, a highly basic, cytplasmic peptide that plays a role in mitotic re-entry during adult morphogenesis. Expressed in a variety of tissues with highest expression in thymus, spleen and heart, HECA is thought to play a role in the development of epithelial tube networks in lung tissue and may also be involved in the pathogenesis of lung cancer. The gene encoding HECA maps to human chromosome 6, which contains 170 million base pairs and comprises nearly 6 % of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.

    Gene ID
    51696
    UniProt
    Q9UBI9
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