Calnexin antibody (C-Term)
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- Target See all Calnexin (CANX) Antibodies
- Calnexin (CANX)
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Binding Specificity
- C-Term
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Reactivity
- Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, Pig, Monkey, Sheep, Hamster, Chicken, Avian, Horse, Goat, Cat, Donkey
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Host
- Goat
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Clonality
- Polyclonal
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Conjugate
- This Calnexin antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificity
- Detects a band of 90 kDa by Western blot in the following human (293A, primary fibroblasts, HaCat, HeLa, HMEC-1, Jurkat, MNT1, U-118, rat (TR-iBRB), mouse (3T3, AtT-20, Hepa, Raw264.7), monkey (COS-7) and canine (D17) whole cell lysates.
- Characteristics
- Calnexin
- Purification
- epitope affinity purified
- Immunogen
- Purified recombinant peptide within residues 550 aa to the C-terminus of human CANX produced in E. coli.
- Isotype
- IgG
- Top Product
- Discover our top product CANX Primary Antibody
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- Restrictions
- For Research Use only
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- Concentration
- 2 mg/mL
- Buffer
- Polyclonal antibody supplied as a 200 µL (2 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide
- Handling Advice
- The antibody solution should be gently mixed before use.
- Storage
- 4 °C,-20 °C
- Storage Comment
- For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.
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Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance." in: Scientific reports, Vol. 7, Issue 1, pp. 1698, (2018) (PubMed).
: "Host cell autophagy contributes to Plasmodium liver development." in: Cellular microbiology, Vol. 18, Issue 3, pp. 437-50, (2016) (PubMed).
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Methylglyoxal-induced glycation changes adipose tissue vascular architecture, flow and expansion, leading to insulin resistance." in: Scientific reports, Vol. 7, Issue 1, pp. 1698, (2018) (PubMed).
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- Target
- Calnexin (CANX)
- Alternative Name
- CANX (CANX Products)
- Synonyms
- CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody
- Background
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CANX is a member of the calnexin family of molecular chaperones. This protein is a calcium-binding, ER-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation.
Synonyms: Calnexin, CALX, CNX, FLJ26570, histocompatibility complex class I antigen binding protein p88, IP90, major histocompatibility complex class I antigen-binding protein p88, MS952, P90 antibody.
Ensembl identifier: ENSG00000127022 - Pathways
- MAPK Signaling, Thyroid Hormone Synthesis
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