CHM antibody (AA 1-80)

Catalog No. ABIN1440017

Product Details anti-CHM Antibody

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Binding Specificity: AA 1-80

Reactivity: Human, Rat, Mouse, Horse, Cow, Pig, Dog, Rabbit, Donkey, Goat, Sheep, Guinea Pig, Hamster, Cat, Monkey, Chicken, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This CHM antibody is un-conjugated

Application: Western Blotting (WB)

Specificity: Detects endogenous Rep1 and in transfected cells by Western blot.

Characteristics: Choroideremia (Rab escort protein 1)

Purification: epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 1-80 aa at the N-terminus of rat Rep1 produced in E. coli.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (3 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for CHM

Target: CHM (Choroideremia (Rab Escort Protein 1) (CHM))

Alternative Name: REP1 (CHM Products)

Synonyms: CHM antibody, REP1 antibody, DXS540 antibody, GGTA antibody, HSD-32 antibody, REP-1 antibody, TCD antibody, DKFZp459K2154 antibody, tcd antibody, ggta antibody, rep-1 antibody, dxs540 antibody, hsd-32 antibody, MGC68578 antibody, Rep-1 antibody, chm antibody, chm-a antibody, chm-b antibody, chml antibody, CHM, Rab escort protein 1 antibody, choroideremia (Rab escort protein 1) antibody, choroideremia (Rab escort protein 1) L homeolog antibody, choroidermia (RAB escort protein 1) antibody, choroideremia (Rab escort protein 1) S homeolog antibody, CHM antibody, chm antibody, chm.L antibody, Chm antibody, chm.S antibody

Background: REP1 is the component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Mutations in this protein are a cause of a type of retinal degeneration, called choroideremia.
Synonyms: CHM, choroideraemia protein, DXS540, GGTA, HSD-32, RP1-93L7.1, rab escort protein 1, Rab geranylgeranyltransferase component A, REP-1, TCD antibody.
Ensembl identifier: ENSG00000188419

Pathways: Sensory Perception of Sound