N-Cadherin antibody (C-Term)

Catalog No. ABIN1440032

Product Details anti-N-Cadherin Antibody

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Chicken, Cow, Rabbit, Dog, Pig, Monkey, Horse, Sheep, Cat, Donkey, Goat, Guinea Pig, Hamster, Avian

Host: Goat

Clonality: Polyclonal

Conjugate: This N-Cadherin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificity: Detects endogenous levels of total N-cadherin protein by Western blot in the whole cell lysates (COS-7, HeLa, HUH and Hepa-6).

Characteristics: N-Cadherin

Purification: epitope affinity purified

Immunogen: Purified recombinant peptide derived from within residues 850 aa to C-terminus of human CDH2 produced in E. coli.

Isotype: IgG

Application Details

Restrictions: For Research Use only

Handling

Concentration: 3 mg/mL

Buffer: Polyclonal antibody supplied as a 200 µL (3 mg/mL) aliquot in PBS, 20 % glycerol and 0.05 % sodium azide

Handling Advice: The antibody solution should be gently mixed before use.

Storage: 4 °C,-20 °C

Storage Comment: For continuous use, store at 2-8 deg,C for one-two days. For extended storage, store in -20 deg,C freezer. Working dilution samples should be discarded if not used within 12 hours.

Target Details for N-Cadherin

Target: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Alternative Name: CDH2 (CDH2 Products)

Synonyms: CD325 antibody, CDHN antibody, CDw325 antibody, NCAD antibody, N-cadherin antibody, cadherin-2 antibody, cdhn antibody, ncad antibody, cdw325 antibody, CDH2 antibody, Cadherin-2 antibody, Ncad antibody, glo antibody, lyr antibody, pac antibody, wu:fb47h04 antibody, cadherin 2 antibody, cadherin 2 S homeolog antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, CDH2 antibody, cdh2.S antibody, cdh2 antibody, Cdh2 antibody

Background: CDH2 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one trans membrane domain, and a highly conserved intracellular domain. It has been shown to play an essential role in normal neuronal development, which is implicated in an array of processes including neuronal differentiation, migration, axon growth and fasciculation.
Synonyms: cadherin 2, cadherin-2, CD325, CDHN, CDw325, CDH2, NCAD, N-cadherin, N-cadherin 1, neural cadherin, neural-cadherin, neural cadherin (NCAD) antibody.
Ensembl identifier: ENSG00000170558

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane