Advillin antibody (Middle Region)

Catalog No. ABIN1449868

Product Details anti-Advillin Antibody

Target: Advillin (AVIL)

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Advillin antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QELPEDVNPA KKENYLSEQD FVSVFGITRG QFAALPGWKQ LQMKKEKGLF

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Dog, Bovine, Horse, RabbitSpecies reactivity (tested):Human

Purification: Purified using peptide immunoaffinity column

Immunogen: Synthetic peptide directed towards the middle region of human AVIL

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Reconstitution: Add 50 μL of distilled water to a final concentration of 1 mg/mL.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store lyophilized at 2-8 °C or at -20 °C long term. After reconstitution store the antibody undiluted at 2-8 °C for up to one month or in aliquots at -20 °C long term.

Target Details for Advillin

Target: Advillin (AVIL)

Alternative Name: Advillin (AVIL Products)

Synonyms: Adv antibody, SpAdv antibody, villin antibody, zgc:136857 antibody, ADVIL antibody, DOC6 antibody, p92 antibody, Advil antibody, advillin antibody, AVIL antibody, adv antibody, avil antibody, CpipJ_CPIJ004696 antibody, Avil antibody

Background: AVIL is a member of the gelsolin/villin family of actin regulatory proteins. This protein has structural similarity to villin. It binds actin and may play a role in the development of neuronal cells that form ganglia. Avil is a Ca2+-regulated actin-binding protein. It may have a unique function in the morphogenesis of neuronal cells which form ganglia. It is required for SREC1-mediated regulation of neurite-like outgrowth. It plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. It is involved in the formation of long fine actin-containing filopodia-like structures in fibroblast and is required for SREC1-mediated regulation of neurite-like outgrowth. Avil plays a role in ciliogenesis.Synonyms: AVIL, p92

Gene ID: 10677

NCBI Accession: NP_006567

Pathways: Regulation of Actin Filament Polymerization