CASK antibody (N-Term)

Catalog No. ABIN1449948

Product Details anti-CASK Antibody

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CASK antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse, Rat.

Purification: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid synthetic peptide near the amino terminus of Human CASK

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CASK

Target: CASK (Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK))

Alternative Name: CASK (CASK Products)

Synonyms: CAKI antibody, CAMGUK antibody, CG13412 antibody, CG13413 antibody, CG6703 antibody, CMG antibody, CMG/CASK antibody, Caki antibody, CamGUK antibody, CamguK antibody, Camguk antibody, Cask antibody, Cmg antibody, DLin-2 antibody, Dmel\\CG6703 antibody, RE09582p antibody, caki antibody, camguk antibody, cmg antibody, dCASK antibody, wu:fb70g06 antibody, CAGH39 antibody, FGS4 antibody, LIN2 antibody, MICPCH antibody, MRXSNA antibody, TNRC8 antibody, DXPri1 antibody, DXRib1 antibody, LIN-2 antibody, Pals3 antibody, mLin-2 antibody, CG6703 gene product from transcript CG6703-RF antibody, Peripheral plasma membrane protein CASK antibody, CAMK/CASK protein kinase antibody, peripheral plasma membrane protein CASK antibody, calcium/calmodulin-dependent serine protein kinase b antibody, calcium/calmodulin-dependent serine protein kinase a antibody, calcium/calmodulin dependent serine protein kinase antibody, calcium/calmodulin-dependent serine protein kinase (MAGUK family) antibody, calcium/calmodulin-dependent serine protein kinase (MAGUK family) S homeolog antibody, CASK antibody, Bm1_33725 antibody, LOAG_17286 antibody, Tsp_03763 antibody, caskb antibody, caska antibody, Cask antibody, cask.S antibody

Background: CASK (Calcium/calmodulin-dependent serine protein kinase), a conserved multi-domain scaffolding protein, belongs to a MAGUK (membrane-associated guanylate kinase homologs) subfamily and is involved in cell junction organization, tumor suppression and signaling. It is characterized by a novel domain structure that consists of a calcium/calmodulin-dependent protein kinase domain followed by PDZ, SH3 and guanylate kinase-like (GUK) domains. CASK is ubiquitously expressed and significantly greater in brain where it is thought to be involved in signaling at neuronal synapses. CASK interacts with CASKINs and defects in CASK are the cause of mental retardation X-linked CASK-related.Synonyms: Calcium/calmodulin-dependent serine protein kinase, LIN2, Lin-2 homolog, Peripheral plasma membrane protein CASK

Gene ID: 8573

NCBI Accession: NP_003679

Pathways: Synaptic Vesicle Exocytosis