SAMSN1 antibody (C-Term)

Catalog No. ABIN1450036

Product Details anti-SAMSN1 Antibody

Target: SAMSN1 (SAM Domain, SH3 Domain and Nuclear Localization Signals, 1 (SAMSN1))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SAMSN1 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Purification: Affinity chromatography purified via peptide column

Immunogen: Rabbit polyclonal SAMSN antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SAMSN.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody (in aliquots) at -20 °C.

Target Details for SAMSN1

Target: SAMSN1 (SAM Domain, SH3 Domain and Nuclear Localization Signals, 1 (SAMSN1))

Alternative Name: SAMSN1 (SAMSN1 Products)

Background: SAMSN (HACS1) is a member of a novel gene family of putative adaptors and scaffold proteins containing SH3 and SAM (sterile alpha motif) domains. It encodes a 441 amino acid protein that is differentially expressed in hematopoietic cells and malignancies including myeloid leukemia, lymphoma, and myeloma. SAMSN has restricted expression in human tissues. It has been shown to be up-regulated by B cell activation signals and is a participant in B cell activation and differentiation. SAMSN is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy.Synonyms: HACS1, Hematopoietic adaptor containing SH3 and SAM domains 1, SAM domain SH3 domain and nuclear localization signals protein 1, SAM domain-containing protein SAMSN-1, SAMSN-1, SH3-SAM adaptor protein

Molecular Weight: 41 kDa

Gene ID: 64092

NCBI Accession: NP_071419